Articles with "ldd2269" as a keyword



Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity

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Published in 2017 at "Investigational New Drugs"

DOI: 10.1007/s10637-017-0496-2

Abstract: SummaryLysine (K)-specific demethylase 4A (KDM4A) is a histone demethylase that removes methyl residues from trimethylated or dimethylated histone 3 at lysines 9 and 36. Overexpression of KDM4A is found in various cancer types. To identify… read more here.

Keywords: demethylase; ldd2269; kdm4a; novel inhibitors ... See more keywords