Toxic impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.11.035
Abstract: The use of anabolic androgenic steroids (AASs) among non-athletes is a public health-problem, as abusers underestimate the negative effects associated with these drugs. The present study investigated the toxic effects of testosterone, nandrolone, stanozolol, and… read more here.
Keywords: androgenic steroids; toxic impact; ldh release; cell ... See more keywords
An investigation on 3-acetyl-7-methoxy-coumarin Schiff bases and their Ru(II) metallates with potent antiproliferative activity and enhanced LDH and NO release
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c7ra12104k
Abstract: New cyclometallated ruthenium(II) complexes of 3-acetyl-7-methoxycoumarin-4N-substituted thiosemicarbazones were synthesized and characterized by analytical and spectral techniques. The crystal structures of the ligands H2L1–3 and complexes (1, 2 and 4) were confirmed by X-ray crystallography. The… read more here.
Keywords: ldh release; acetyl methoxy; investigation acetyl; methoxy coumarin ... See more keywords
Impact of serum in cell culture media on in vitro lactate dehydrogenase (LDH) release determination
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Computational Biology"
DOI: 10.3233/jcb-179002
Abstract: Cell exposure to cytotoxic substrates can cause decreased cell viability or cellular death through necrosis or apoptosis. The common characteristic of both reaction patterns (necrosis and apoptosis) is a compromised or damaged cell membrane, which… read more here.
Keywords: ldh release; cell; lactate dehydrogenase; serum ... See more keywords
Cytoprotective Activity of p-Terphenyl Polyketides and Flavuside B from Marine-Derived Fungi against Oxidative Stress in Neuro-2a Cells
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26123618
Abstract: The influence of p-terphenyl polyketides 1–3 from Aspergillus candidus KMM 4676 and cerebroside flavuside B (4) from Penicillium islandicum (=Talaromyces islandicus) against the effect of neurotoxins, rotenone and paraquat, on Neuro-2a cell viability by MTT… read more here.
Keywords: paraquat treated; treated cells; viability; ldh release ... See more keywords
Neuroprotective effects of midazolam on focal cerebral ischemia in rats through anti‑apoptotic mechanisms.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2018.3973
Abstract: Stroke is a cerebrovascular circulatory disorder and its high mortality rate represents a prominent threat to human health. Subsequent apoptosis and cytotoxicity are the main causes underlying the poor prognosis. Midazolam (MDZ) is a benzodiazepine… read more here.
Keywords: neuroprotective effects; apoptosis; effects midazolam; ldh release ... See more keywords