Inhibition of LDHA to Induce EEF2 Release Enhances Thrombocytopoiesis.
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DOI: 10.1182/blood.2022015620
Abstract: Translation is essential for megakaryocyte (MK) maturation and platelet production. However, how the translational pathways are regulated in this process remains unknown. In this study, we found that megakaryocyte/platelet-specific lactate dehydrogenase A (LdhA)-knockout mice showed… read more here.
Keywords: inhibition ldha; ldha induce; maturation; platelet ... See more keywords