A Western-style diet interacts with genetic variants of the LDL receptor to hyper-LDL cholesterolemia in Korean adults
Sign Up to like & getrecommendations! Published in 2020 at "Public Health Nutrition"
DOI: 10.1017/s1368980020001305
Abstract: Abstract Objective: To evaluate the association of genetic risk scores (GRS) of LDLR, APOB and proprotein convertase subtilisin-kexin type 9 (PCSK9) SNP and plasma LDL concentrations and to identify lifestyle interactions with the GRS in… read more here.
Keywords: style; genetic variants; ldl concentrations; western style ... See more keywords
Low-density Lipoprotein Cholesterol and Risk of Intracerebral Hemorrhage: A Prospective Study, Systematic Review, and Meta-analysis (P18-029-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz039.p18-029-19
Abstract: Objectives To prospectively examine the association between low density lipoprotein cholesterol (LDL-C) concentrations and intracerebral hemorrhage (ICH) risk, and test the association in a meta-analysis combining the present data with previous studies. Methods The current… read more here.
Keywords: meta analysis; density lipoprotein; risk; ldl concentrations ... See more keywords
Validation of the Martin method to estimate low-density lipoprotein cholesterol concentrations in Japanese populations and a modified method for laboratory information system application
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical Biochemistry"
DOI: 10.1177/00045632221098870
Abstract: Objectives High concentrations of low-density lipoprotein cholesterol (LDL-C) are a risk factor for cardiovascular disease. We validated the efficacy of the Martin method is useful in the estimation of LDL-C concentrations was validated in Japanese… read more here.
Keywords: ldl concentrations; modified martin; method; martin method ... See more keywords
LDL-C Concentrations and the 12-SNP LDL-C Score for Polygenic Hypercholesterolaemia in Self-Reported South Asian, Black and Caribbean Participants of the UK Biobank
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.845498
Abstract: Background: Monogenic familial hypercholesterolaemia (FH) is an autosomal dominant disorder characterised by elevated low-density lipoprotein cholesterol (LDL-C) concentrations due to monogenic mutations in LDLR, APOB, PCSK9, and APOE. Some mutation-negative patients have a polygenic cause… read more here.
Keywords: ldl concentrations; snp score; hypercholesterolaemia; ethnic groups ... See more keywords