Amino acid starvation‐induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance
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DOI: 10.15252/embr.202153373
Abstract: Mammalian cells utilize Akt‐dependent signaling to deploy intracellular Glut4 toward cell surface to facilitate glucose uptake. Low‐density lipoprotein receptor (LDLR) is the cargo receptor mediating endocytosis of apolipoprotein B‐containing lipoproteins. However, signaling‐controlled regulation of intracellular… read more here.
Keywords: acid starvation; amino acid; endocytosis; ldlr trafficking ... See more keywords