Eight weeks of ledipasvir/sofosbuvir is effective for selected patients with genotype 1 hepatitis C virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29005
Abstract: Eight weeks duration of ledipasvir/sofosbuvir (LDV/SOF) can be considered in genotype 1 hepatitis C virus–infected patients who are treatment‐naive, do not have cirrhosis, and have a pretreatment viral load read more here.
Keywords: ldv sof; eight weeks; treatment; relapse ... See more keywords
A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: THE PRIORITIZE STUDY.
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DOI: 10.1002/hep.32053
Abstract: BACKGROUND & AIMS Multiple direct-acting antiviral (DAA) regimens are available to treat hepatitis C virus (HCV), genotype 1 infection. However, comparative effectiveness from randomized controlled trials of DAA regimens is unavailable. Approach & Results We… read more here.
Keywords: trial; randomized controlled; ldv sof; hepatitis ... See more keywords
Effectiveness of ledipasvir/sofosbuvir in real-world patients with chronic hepatitis C: a collaborative treatment approach.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.01.016
Abstract: The effectiveness of ledipasvir/sofosbuvir (LDV/SOF) in routine use in clinical practice for the management of chronic hepatitis C virus (HCV) has not been well described. Data with prior agents suggest that management of HCV using… read more here.
Keywords: chronic hepatitis; ldv sof; treatment; effectiveness ledipasvir ... See more keywords
Resistance-associated substitution and ledipasvir/sofosbuvir therapy in Mongolian chronic hepatitis C patients.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.10.003
Abstract: BACKGROUND Mongolia has the highest prevalence of hepatitis C virus (HCV) infection worldwide. Ledipasvir/sofosbuvir (LDV/SOF) was introduced to Mongolia since 2016 for HCV eradication. It has been reported that HCV resistance-associated substitutions (RASs) would affect… read more here.
Keywords: ldv sof; hepatitis; treatment; ldv ... See more keywords
Hepatitis C Virus Treatment Response to Ledipasvir/Sofosbuvir Among Patients Co-Infected with HIV and HCV: Real-world Data in a Black Population
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DOI: 10.1093/ofid/ofx163.1754
Abstract: Abstract Background Treatment of Hepatitis C virus (HCV) infection for patients with Human Immunodeficiency Virus (HIV) has improved with direct acting antivirals (DAAs). However, outcomes among Black persons treated with ledipasvir/sofosbuvir (LDV/SOF) may be inferior… read more here.
Keywords: ldv sof; treatment; speaker; hiv hcv ... See more keywords
Uptake of Hepatitis C Virus Treatment in a Multi-State Medicaid Population, 2013 - 2017.
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DOI: 10.1111/1475-6773.13994
Abstract: OBJECTIVE To examine trends in direct acting antiviral (DAA) uptake in a multi-state Medicaid population with hepatitis C virus (HCV) prior to and after ledipasvir/sofosbuvir (LDV/SOF) approval and changes in prior authorization (PA) requirements. DATA… read more here.
Keywords: ldv sof; uptake; treatment; approval ... See more keywords
Sustainable and equivalent improvements in symptoms and functional well‐being following viral cure from ledipasvir/sofosbuvir versus elbasvir/grazoprevir for chronic hepatitis C infection: Findings from the randomized PRIORITIZE trial
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DOI: 10.1111/jvh.13716
Abstract: The PRIORITIZE trial (clinicaltrials.gov: NCT02786537) was the first comparative effectiveness study to directly compare ledipasvir/sofosbuvir (LDV/SOF) and elbasvir/grazoprevir (EBR/GZR) for the treatment of chronic hepatitis C virus (HCV). A secondary aim of this study was… read more here.
Keywords: ldv sof; functional well; trial; symptoms functional ... See more keywords
Efficacy and safety of ledipasvir/sofosbuvir for hepatitis C among drug users: a systematic review and meta-analysis
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DOI: 10.1186/s12985-021-01625-w
Abstract: Background and aims Limited data is available on the efficacy of direct acting anti-viral drugs on hepatitis C in drug users. The aim of this meta-analysis was to comprehensively analyze the efficacy and safety of… read more here.
Keywords: ldv sof; hepatitis; drug users; analysis ... See more keywords
Severe Steroid-responsive Skin Disorders Related to Ledipasvir and Sofosbuvir for HCV
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DOI: 10.2169/internalmedicine.9744-17
Abstract: Combination therapy with ledipasvir and sofosbuvir (LDV/SOF), direct-acting antiviral agents, is highly effective against hepatitis C virus genotype 1 infection. Although LDV/SOF is safer than conventional treatment, reports have indicated that LDV/SOF was discontinued in… read more here.
Keywords: skin disorders; ldv sof; treatment; sof ... See more keywords