Articles with "lead structures" as a keyword



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Exploring the Relationships between Structure and Antimicrobial Potency of Quinolinequinones

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11101397

Abstract: Microorganisms are responsible for hospital infections, and methicillin-resistant Staphylococcus aureus is one of them. In looking for the most effective lead structures to cope with the rise of antimicrobial (antibiotic) resistance, we evaluated the antimicrobial… read more here.

Keywords: lead structures; staphylococcus aureus; activity; gram positive ... See more keywords
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Recent Advances in Discovery of Lead Structures from Microbial Natural Products: Genomics- and Metabolomics-Guided Acceleration

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26092542

Abstract: Natural products (NPs) are evolutionarily optimized as drug-like molecules and remain the most consistently successful source of drugs and drug leads. They offer major opportunities for finding novel lead structures that are active against a… read more here.

Keywords: natural products; advances discovery; discovery lead; lead structures ... See more keywords