Articles with "leading senescence" as a keyword



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NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24108724

Abstract: Alpha-aminoterminal acetyltransferase B (NatB) is a critical enzyme responsible for acetylating the aminoterminal end of proteins, thereby modifying approximately 21% of the proteome. This post-translational modification impacts protein folding, structure, stability, and interactions between proteins… read more here.

Keywords: catalytic subunit; replication; cell cycle; replication initiation ... See more keywords