Feedback Inhibition in Chemical Catalysis Leads the Dynamic Kinetic to Kinetic Resolution in C3-Indolylation of Spiro-epoxyoxindoles.
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DOI: 10.1021/acs.orglett.0c00028
Abstract: The first feedback inhibition, similar to enzyme catalysis, in the Co(III)salen-catalyzed asymmetric ring-opening reaction of N-free spiro-epoxyoxyindole has been discovered, which leads dynamic kinetic to kinetic resolution. This is the first report of the enantioselective… read more here.
Keywords: kinetic kinetic; kinetic resolution; dynamic kinetic; leads dynamic ... See more keywords