Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202528658
Abstract: Engineering nanomaterial‐induced endothelial leakiness (NanoEL) through tumor vasculature gaps allows for enhanced nanotherapeutics entry into tumors. However, current NanoEL strategies require two steps and multiple particle types: first with the NanoEL agent and subsequently with… read more here.
Keywords: engineering; leakiness; tumor; gold nanoclusters ... See more keywords
Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2024 at "Translational Psychiatry"
DOI: 10.1038/s41398-023-02706-w
Abstract: Breakdown of the neurovascular unit is associated with blood-brain barrier (BBB) leakiness contributing to cognitive decline and disease pathology in the early stages of Alzheimer’s disease (AD). Vascular stability depends on angiopoietin-1 (ANGPT-1) signalling, antagonised… read more here.
Keywords: disease; csf angpt; leakiness; csf ... See more keywords
SLE serum induces altered goblet cell differentiation and leakiness in human intestinal organoids
Sign Up to like & getrecommendations! Published in 2024 at "EMBO Molecular Medicine"
DOI: 10.1038/s44321-024-00023-3
Abstract: Human intestinal epithelial cells are the interface between luminal content and basally residing immune cells. They form a tight monolayer that constantly secretes mucus creating a multilayered protective barrier. Alterations in this barrier can lead… read more here.
Keywords: human intestinal; sle; barrier; leakiness ... See more keywords
Leakiness and flow capture ratio of insect pectinate antennae
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DOI: 10.1098/rsif.2019.0779
Abstract: The assumption that insect pectinate antennae, which are multi-scale organs spanning over four orders of magnitude in size among their different elements, are efficient at capturing sexual pheromones is commonly made but rarely thoroughly tested.… read more here.
Keywords: leakiness; flow; flow capture; pectinate ... See more keywords
Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "Beilstein Journal of Nanotechnology"
DOI: 10.3762/bjnano.14.28
Abstract: Nanoparticles (NPs) exhibit unique physicochemical properties that enable them to overcome biological barriers and to be considered one of the best materials with anticancer properties. Most of the administered NPs that end up in the… read more here.
Keywords: metal polymeric; leakiness; mechanism consequences; endothelial leakiness ... See more keywords
Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.7554/elife.90565
Abstract: Like other volume electron microscopy approaches, automated tape-collecting ultramicrotomy (ATUM) enables imaging of serial sections deposited on thick plastic tapes by scanning electron microscopy (SEM). ATUM is unique in enabling hierarchical imaging and thus efficient… read more here.
Keywords: atum; electron microscopy; brain; leakiness ... See more keywords