Response to: Obesity and Vitamin D Metabolism Modifications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3743
Abstract: We thank Landrier and colleagues for their thoughtful comments regarding our recent publication regarding the role of decreased expression of CYP2R1 as a basis for reduced circulating levels of 25(OH)D in obese mice. First, Landrier… read more here.
Keywords: fat diet; obese mice; obesity; mice ... See more keywords
Green tea polyphenols positively impact hepatic metabolism of adiponectin-knockout lean mice
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.103679
Abstract: Abstract Green tea (GT) has health benefits but the mechanism of its biological effects remains poorly known. Adiponectin has been considered a key adipocytokine for protection against hepatic lipid accumulation. We aimed to assess whether… read more here.
Keywords: lean mice; adiponectin knockout; adiponectin; green tea ... See more keywords
Nicotinamide riboside induces a thermogenic response in lean mice
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DOI: 10.1016/j.lfs.2018.09.015
Abstract: Aims: Nicotinamide Riboside (NR) is a NAD+ booster with wide physiological repercussion including the improvement on glucose and lipid homeostasis, increasing the life expectancy in mammals. However, the effects of NR on metabolism are only… read more here.
Keywords: bat; thermogenic response; nicotinamide riboside; mice ... See more keywords
Abstract P173: Trimethylamine N-Oxide (TMAO) Impairs Endothelium-Dependent Relaxation of the Mesenteric Artery in Lean and Db/db Mice
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p173
Abstract: Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite produced from choline and phosphatidylcholine and it has recently been related to risk for cardiovascular diseases. This study tests the hypothesis that TMAO would contribute to impaired… read more here.
Keywords: endothelium dependent; tmao; mice; lean mice ... See more keywords
Abstract P2044: Renoprotective Effects of Canagliflozin in Db/db Diabetic Mice
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DOI: 10.1161/hyp.74.suppl_1.p2044
Abstract: Diabetes is one of the major causes of chronic kidney disease which could lead to end-stage renal disease. Previously, we have shown increased urinary angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db mouse… read more here.
Keywords: effects canagliflozin; renoprotective effects; expression; mice ... See more keywords
Differential progression of unhealthy diet-induced hepatocellular carcinoma in obese and non-obese mice
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DOI: 10.1371/journal.pone.0272623
Abstract: Background Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalence of… read more here.
Keywords: nash hcc; progression; obese mice; mice ... See more keywords