Deep learning identifies DDR1 kinase inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Drug Discovery"
DOI: 10.1038/d41573-019-00170-0
Abstract: New classes of HIV inhibitors that can suppress drugresistant viral variants and exhibit longlasting activity are needed. Here, Yant et al. report the identification of GSCA1, a smallmolecule inhibitor of the HIV-1 capsid protein. In… read more here.
Keywords: kinase inhibitors; learning identifies; ddr1 kinase; deep learning ... See more keywords
Unsupervised deep learning identifies semantic disentanglement in single inferotemporal face patch neurons
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26751-5
Abstract: In order to better understand how the brain perceives faces, it is important to know what objective drives learning in the ventral visual stream. To answer this question, we model neural responses to faces in… read more here.
Keywords: identifies semantic; deep learning; face; learning identifies ... See more keywords
Deep learning identifies and quantifies recombination hotspot determinants
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac234
Abstract: MOTIVATION Recombination is one of the essential genetic processes for sexually reproducing organisms, which can happen more frequently in some regions, called recombination hotspots. Although several factors, such as PRDM9 binding motifs, are known to… read more here.
Keywords: identifies quantifies; recombination hotspot; hotspot; learning identifies ... See more keywords
Deep Learning Identifies Cardiomyocyte Nuclei With High Precision.
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/circresaha.120.316672
Abstract: Correspondence to: Steve Jiang, PhD, Medical Artificial Intelligence and Automation Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center, 2280 Inwood Rd, Dallas, TX 75390, Email [email protected]; or Hesham A. Sadek, MD, PhD,… read more here.
Keywords: learning identifies; high precision; identifies cardiomyocyte; cardiomyocyte nuclei ... See more keywords