The pivotal role of glycogen synthase kinase 3 (GSK-3) in vomiting evoked by specific emetogens in the least shrew (Cryptotis parva)
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry international"
DOI: 10.1016/j.neuint.2019.104603
Abstract: Glycogen synthase kinase 3 (GSK-3) is a constitutively active multifunctional serine-threonine kinase which is involved in diverse physiological processes. GSK-3 has been implicated in a wide range of diseases including neurodegeneration, inflammation, diabetes and cancer.… read more here.
Keywords: glycogen synthase; kinase; kinase gsk; synthase kinase ... See more keywords
New Records of the Least Shrew (Cryptotis parva floridana) from Key Largo, Florida
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DOI: 10.1656/058.020.0209
Abstract: Abstract Cryptotis parva (Least Shrew) is an insectivore that is widely distributed across peninsular Florida but has only twice been captured in the Florida Keys, both times on the island of Key Largo, Monroe County.… read more here.
Keywords: cryptotis parva; least shrew; largo; key largo ... See more keywords
Evidence for Bell-Shaped Dose-Response Emetic Effects of Temsirolimus and Analogs: The Broad-Spectrum Antiemetic Efficacy of a Large Dose of Temsirolimus Against Diverse Emetogens in the Least Shrew (Cryptotis parva)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.848673
Abstract: Temsirolimus is a prodrug form of sirolimus (rapamycin). With its analogs (everolimus, ridaforolimus, and rapamycin), it forms a group of anticancer agents that block the activity of one of the two mammalian targets of rapamycin… read more here.
Keywords: shaped dose; least shrew; dose temsirolimus; bell shaped ... See more keywords