A serine protease-associated lectin in the cytolytic system of blowfly (Chrysomya megacephala) larvae: Evidence and characterization.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21623
Abstract: Cytolytic activity against invading microorganisms is one of the innate forms of immunity in invertebrates. A serine protease-associated sialic acid-specific cytolytic lectin was purified using glutaraldehyde-fixed ox erythrocytes from the larval extract of blowfly (Chrysomya… read more here.
Keywords: serine protease; lectin; protease associated; blowfly ... See more keywords
Lectin‐based phototherapy targeting cell surface glycans for pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34362
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is resistant to current treatments but lectin‐based therapy targeting cell surface glycans could be a promising new horizon. Here, we report a novel lectin‐based phototherapy (Lec‐PT) that combines the PDAC targeting… read more here.
Keywords: cell; pancreatic cancer; lectin; targeting cell ... See more keywords
Thermoresponsive Glycopolypeptide Containing Block Copolymers, Particle Formation and Lectin Interaction.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100518
Abstract: Amphiphilic block copolymers with a thermoresponsive poly(N-isopropylacrylamide) block and a glycopeptide block were synthesized and particle formation as well as interaction of the glyco-corona with lectins was investigated. The synthetic route comprises the preparation of… read more here.
Keywords: interaction; pga pnipam; particle formation; lectin ... See more keywords
Application of Lectin Microarrays for Biomarker Discovery
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DOI: 10.1002/open.201900326
Abstract: Abstract Many proteins in living organisms are glycosylated. As their glycan patterns exhibit protein‐, cell‐, and tissue‐specific heterogeneity, changes in the glycosylation levels could serve as useful indicators of various pathological and physiological states. Thus,… read more here.
Keywords: biomarker discovery; microarrays biomarker; lectin; lectin microarrays ... See more keywords
Purification and Functional Characterization of the Effects on Cell Signaling of Mytilectin: A Novel β-Trefoil Lectin from Marine Mussels.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0430-4_21
Abstract: In the 2010s, a novel lectin family with β-trefoil folding has been identified in marine mussels from the family Mytilidae (phylum Mollusca). "MytiLec-1," the lectin described in this chapter, was the first member of this… read more here.
Keywords: lectin; marine mussels; family; purification functional ... See more keywords
Production and Characterization of MIC1: A Lectin from Toxoplasma gondii.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0430-4_38
Abstract: Some lectins of pathogens interact with host cells through the recognition of specific carbohydrates displayed on the mammals' cell surface. The microneme protein 1 (MIC1) from Toxoplasma gondii has a lectin domain that specifically binds… read more here.
Keywords: mic1; production; gondii; lectin ... See more keywords
Expression and Purification of a Human Pluripotent Stem Cell-Specific Lectin Probe, rBC2LCN.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0430-4_44
Abstract: rBC2LCN is a recombinant N-terminal domain of BC2L-C lectin that is derived from the gram-negative bacteria Burkholderia cenocepacia and specifically binds to Fucα1-2Galβ1-3GlcNAc/GalNAc. Glycome analysis using a high-density lectin microarray revealed that rBC2LCN specifically binds… read more here.
Keywords: human pluripotent; rbc2lcn; probe; lectin ... See more keywords
Lectin Histochemistry for Tissues and Cells, and Dual Lectin and Antibody Co-localization.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1685-7_14
Abstract: In this chapter we describe in detail methods for lectin staining of (1) tissues, and (2) cells to identify and map endogenous glycosylation. We also describe (3) dual antibody and lectin staining of tissues to… read more here.
Keywords: tissues cells; lectin histochemistry; antibody; lectin ... See more keywords
Lectin Histochemistry: Historical Perspectives, State of the Art, and the Future.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6788-9_6
Abstract: Lectins, discovered more than 100 years ago and defined by their ability to selectively recognize specific carbohydrate structures, are ubiquitous in living organisms. Their precise functions are as yet under-explored and incompletely understood but they… read more here.
Keywords: histochemistry historical; perspectives state; lectin histochemistry; lectin ... See more keywords
Mannose-binding lectin gene polymorphisms in the East Siberia and Russian Arctic populations
Sign Up to like & getrecommendations! Published in 2020 at "Immunogenetics"
DOI: 10.1007/s00251-020-01175-5
Abstract: Mannose-binding lectin (MBL) encoded by MBL2 gene is a protein with the ability to form carbohydrate complexes with microbial wall promoting their subsequent elimination. Genetically determined levels of MBL can modify the risk and clinical… read more here.
Keywords: binding lectin; lectin; mannose binding; nenets dolgan ... See more keywords
Insights into the effects of glycosylation and the monosaccharide-binding activity of the plant lectin CrataBL
Sign Up to like & getrecommendations! Published in 2017 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-017-9766-7
Abstract: CrataBL is a glycoprotein isolated from Crataeva tapia bark, containing two N-glycosylation sites. It has been identified to present lectin activity with some specificity for binding glucose over galactose. However, to date, no information on… read more here.
Keywords: effects glycosylation; monosaccharide binding; cratabl; lectin ... See more keywords