Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20180131
Abstract: To investigate whether the human anti-thrombospondin type 1 domain-containing 7A (THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin complement pathway. Automatic biochemical apparatus was used to assess renal function of mice. The serum… read more here.
Keywords: complement pathway; lectin complement; thsd7a; human anti ... See more keywords
Ficolin‐3 and MASP‐2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency
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DOI: 10.1111/sji.13249
Abstract: Herewith, we provide novel original data about the prevalence of FCN3 rs532781899 and MASP2 rs72550870 variants among the newborns of aboriginal Siberian Arctic populations (Nenets and Dolgan‐Nganasans) and Russians of East Siberia. This novel data… read more here.
Keywords: lectin complement; prevalence; ficolin; gene ... See more keywords