Carbohydrate–Lectin Interactions: An Unexpected Contribution to Affinity
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201600615
Abstract: Uropathogenic E. coli exploit PapG‐II adhesin for infecting host cells of the kidney; the expression of PapG‐II at the tip of bacterial pili correlates with the onset of pyelonephritis in humans, a potentially life‐threatening condition. It… read more here.
Keywords: papg; lectin interactions; carbohydrate lectin; affinity ... See more keywords
Single-molecule imaging of glycan–lectin interactions on cells with Glyco-PAINT
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DOI: 10.1038/s41589-021-00896-2
Abstract: Most lectins bind carbohydrate ligands with relatively low affinity, making the identification of optimal ligands challenging. Here we introduce a point accumulation in nanoscale topography (PAINT) super-resolution microscopy method to capture weak glycan–lectin interactions at… read more here.
Keywords: lectin interactions; paint; microscopy; glyco paint ... See more keywords
Glycan-Lectin Interactions as Novel Immunosuppression Drivers in Glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116312
Abstract: Despite diagnostic and therapeutic improvements, glioblastoma (GB) remains one of the most threatening brain tumor in adults, underlining the urgent need of new therapeutic targets. Lectins are glycan-binding proteins that regulate several biological processes through… read more here.
Keywords: interactions novel; novel immunosuppression; glycan lectin; immunosuppression drivers ... See more keywords