Establishment of a 1, 4, 7, 10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono-N-hydroxysuccinimide ester (DOTA-NHS-ester) based lectin microarray for efficiently detecting serum glycans in gastric cancers.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113686
Abstract: Development of cancers is involved in changes of a variety of glycans. Lectin microarray is one of the most powerful methodologies for investigation of glycan alterations in biological samples with its advantages of high through-put,… read more here.
Keywords: dota nhs; tetraazacyclododecane tetraacetic; lectin microarray; ester ... See more keywords
Comprehensive analysis of glycosphingolipid glycans by lectin microarrays and MALDI-TOF mass spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Nature protocols"
DOI: 10.1038/s41596-021-00544-y
Abstract: Glycosphingolipids (GSLs) are ubiquitous glycoconjugates present on the cell membrane; they play significant roles in many bioprocesses such as cell adhesion, embryonic development, signal transduction and carcinogenesis. Analyzing such amphiphilic molecules is a major challenge… read more here.
Keywords: comprehensive analysis; analysis; lectin microarray; mass spectrometry ... See more keywords
A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
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DOI: 10.1080/19420862.2024.2304268
Abstract: ABSTRACT Glycosylation plays a crucial role in determining the quality and efficacy of therapeutic antibodies. This necessitates a thorough analysis and monitoring process to ensure consistent product quality during manufacturing. In this study, we introduce… read more here.
Keywords: microarray; lectin microarray; glycan profiling; tailored lectin ... See more keywords
Retrospective screening of serum IgG glycosylation biomarker for primary Sjögren’s syndrome using lectin microarray
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DOI: 10.7717/peerj.14853
Abstract: Background Primary Sjögren’s syndrome (PSS) is a systemic autoimmune disease resulting in significant loss of systemic gland secretory function. IgG glycosylation abnormalities had been found to play important roles in autoimmune diseases. Here, we aim… read more here.
Keywords: serum igg; lectin microarray; igg glycosylation; glycosylation ... See more keywords