Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport
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DOI: 10.18632/oncotarget.16002
Abstract: Leelamine is an anticancer chemotherapeutic agent inhibiting intracellular cholesterol transport. Cell death mediated by leelamine occurs due to the lysosomotropic property of the compound, its accumulation in the lysosome, and inhibition of cholesterol transport leading… read more here.
Keywords: leelamine; intracellular cholesterol; cholesterol; cholesterol transport ... See more keywords