Consistent LEF-1 and MYB Immunohistochemical Expression in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma: A Potential Diagnostic Pitfall
Sign Up to like & getrecommendations! Published in 2018 at "Head and Neck Pathology"
DOI: 10.1007/s12105-018-0951-1
Abstract: Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC) is a distinct, newly-described sinonasal tract neoplasm characterized by a salivary gland tumor-like appearance with myoepithelial and ductal cells, frequent surface squamous dysplasia, and relatively indolent behavior. When… read more here.
Keywords: lef; multiphenotypic sinonasal; related multiphenotypic; expression ... See more keywords
Lipidic cubic-phase leflunomide nanoparticles (cubosomes) as a potential tool for breast cancer management
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2079770
Abstract: Abstract Despite the fact of availability of several treatments for breast cancer, most of them fail to attain the desired therapeutic response due to their poor bioavailability, high doses, non-selectivity and as a result systemic… read more here.
Keywords: leflunomide; lef; breast cancer; cancer management ... See more keywords
1365. In Vitro Activity of Lefamulin (LEF) Against Bacterial Pathogens Causing Community-Acquired Bacterial Pneumonia (CABP): SENTRY Surveillance 2016 Results From Asia-Pacific (APAC) and Latin America (LA)
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DOI: 10.1093/ofid/ofy210.1196
Abstract: Abstract Background LEF, a novel pleuromutilin antibiotic for IV and oral use, recently completed a phase 3 trial for the treatment of CABP in adults where it demonstrated noninferiority to moxifloxacin ± linezolid. LEF selectively… read more here.
Keywords: shareholder; lef; vitro activity; cabp ... See more keywords
SAT0518 The role of leflunomide in the treatment of giant cell arteritis
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DOI: 10.1136/annrheumdis-2018-eular.2751
Abstract: Background Glucocorticoids (GC) have been the mainstay treatment in giant cell arteritis (GCA) for decades. Recently tocilizumab and abatacept have been proven to be effective alternatives to glucocortiocids. However, not all GCA patients are eligible… read more here.
Keywords: giant cell; lef; treatment; cell arteritis ... See more keywords
SAT0131 CARDIO- AND CEREBROVASCULAR RISK WITH CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS (CSDMARDS) IN RHEUMATOID ARTHRITIS (RA): A REAL-WORLD COMPARATIVE ASSESSMENT
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.3463
Abstract: Background: RA is associated with an increased cardiovascular (CV) risk. csDMARDs are first-line treatments for RA and can mitigate this risk, but limited data exist on their CV effects. Previous trials have reported protective effects… read more here.
Keywords: hcq; mtx; risk; lef ... See more keywords
Effectiveness and safety of leflunomide compared with cyclophosphamide as induction therapy in Takayasu’s arteritis: an observational study
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DOI: 10.1177/2040622320922019
Abstract: Aims: The objective of this study was to investigate the outcomes of leflunomide (LEF) compared with those of cyclophosphamide (CYC) as induction against active Takayasu’s arteritis (TA) in Chinese patients. Methods: This was an observational… read more here.
Keywords: lef; study; compared cyclophosphamide; induction ... See more keywords
Effectiveness and safety of methotrexate versus leflunomide in 12-month treatment for Takayasu arteritis
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DOI: 10.1177/2040622320975233
Abstract: Aims: The study investigates the effectiveness and safety of methotrexate (MTX) versus leflunomide (LEF) in 12-month treatment of Takayasu arteritis (TAK). Methods: This was a cohort study. Patients diagnosed with TAK between 1 January 2013… read more here.
Keywords: effectiveness safety; lef; treatment; group ... See more keywords
Retrospective analysis of leflunomide and low-dose methylprednisolone for the treatment of diabetic nephropathy combined with membranous nephropathy
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DOI: 10.3389/fendo.2022.941215
Abstract: Diabetic kidney disease (DKD) combined with Membranous Nephropathy (MN) was observed in some patients with the increasing of Diabetic patients. However, no treatment guidelines are available for DKD combined with MN. In this study, we… read more here.
Keywords: dkd; lef group; lef; treatment ... See more keywords