Silencing of long noncoding RNA LEF1‐AS1 prevents the progression of hepatocellular carcinoma via the crosstalk with microRNA‐136‐5p/WNK1
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29503
Abstract: Long noncoding RNAs (lncRNAs) have been recognized as cancer‐associated biological molecules, favoring hepatocellular carcinoma (HCC) progression. This study was conducted to elucidate the effects lncRNA lymphoid enhancer‐binding Factor 1 antisense RNA (LEF1‐AS1) on the pathological… read more here.
Keywords: hcc; wnk1; lncrna lef1; lef1 as1 ... See more keywords
Cancer-testis non-coding RNA LEF1-AS1 regulates the nuclear translocation of PDCD5 and suppresses its interaction with p53 signaling: A novel target for immunotherapy in esophageal squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Carcinogenesis"
DOI: 10.1093/carcin/bgad006
Abstract: Despite the improvement of current classical treatment, the prognosis of esophageal squamous cell carcinoma (ESCC) remains poor. Immunotherapy, as a new treatment method, has revolutionized the therapy of various cancer types and created more attractive… read more here.
Keywords: cancer; lef1 as1; cancer testis;
LEF1-AS1, a long-noncoding RNA, promotes malignancy in glioblastoma
Sign Up to like & getrecommendations! Published in 2017 at "OncoTargets and therapy"
DOI: 10.2147/ott.s130365
Abstract: Objectives The long-noncoding RNAs (lncRNAs) are identified as new crucial regulators of diverse cellular processes in glioblastoma (GBM) tissues. However, the expression pattern and biological function of lncRNAs remain largely unknown. Here, for the first… read more here.
Keywords: long noncoding; gbm; as1; expression ... See more keywords