Lymphoid enhancer binding factor 1 (LEF1) expression is significantly higher in Hodgkin lymphoma associated with Richter syndrome relative to de novo classic Hodgkin lymphoma.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2020.151636
Abstract: Lymphoid enhancer binding factor 1 (LEF1) is consistently upregulated in chronic lymphocytic leukemia (CLL) and in a subset of large B cell lymphoma. Knowledge of LEF1 expression in Hodgkin lymphoma is limited. In this study,… read more here.
Keywords: lymphoma; lef1 expression; hodgkin lymphoma; chl ... See more keywords
NR4A1 promotes LEF1 expression in the pathogenesis of papillary thyroid cancer
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DOI: 10.1038/s41420-022-00843-7
Abstract: The morbidity of papillary thyroid cancer (PTC) is on the rise, but its pathogenesis is still poorly understood. NR4A1 is a transcription factor primarily involving a wide range of pathophysiological responses, but its relationship with… read more here.
Keywords: lef1 expression; expression; papillary thyroid; thyroid cancer ... See more keywords
High expression of LEF1 correlates with poor prognosis in solid tumors, but not blood tumors: a meta-analysis
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DOI: 10.1042/bsr20202520
Abstract: Abstract Background: Previously published studies have indicated that lymphoid enhancer-binding factor 1 (LEF1) expression could be recognized as a valuable biomarker to evaluate clinical outcome for various types of malignant cancer, but the results remained… read more here.
Keywords: expression; meta analysis; prognosis; solid tumors ... See more keywords