The DUB blade goes snicker-snack: Novel ubiquitin cleavage by a Legionella effector protein
Sign Up to like & getrecommendations! Published in 2017 at "Cell Research"
DOI: 10.1038/cr.2017.80
Abstract: Recently, a Legionella pneumophila effector protein was shown to have an unprecedented ATP-independent ubiquitin ligase activity that couples phosphoribosylated ubiquitin (PR-Ub) to serine residues of host proteins. A new study published in Cell Research by… read more here.
Keywords: legionella effector; effector protein; effector; cleavage ... See more keywords
Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC
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DOI: 10.1038/s41467-020-15645-7
Abstract: Protein ubiquitination is one of the most prevalent post-translational modifications, controlling virtually every process in eukaryotic cells. Recently, the Legionella effector MavC was found to mediate a unique ubiquitination through transglutamination, linking ubiquitin (Ub) to… read more here.
Keywords: mavc; legionella effector; effector mavc; ubiquitination ... See more keywords
A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006186
Abstract: Legionella pneumophila, the etiological agent of Legionnaires’ disease, replicates intracellularly in protozoan and human hosts. Successful colonization and replication of this pathogen in host cells requires the Dot/Icm type IVB secretion system, which translocates approximately… read more here.
Keywords: legionella effector; host cytoskeletal; ravk; disrupts host ... See more keywords