Low genomic diversity of Legionella pneumophila within clinical specimens
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2018.03.004
Abstract: Objectives Legionella pneumophila is the leading cause of Legionnaires' disease, a severe form of pneumonia acquired from environmental sources. Investigations of both sporadic cases and outbreaks rely mostly on analysis of a single to a… read more here.
Keywords: diversity; legionella pneumophila; ten isolates; genomic diversity ... See more keywords
Legionella pneumophila LPS to evaluate urinary antigen tests.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.06.013
Abstract: Three urinary antigen tests were compared using purified Legionella pneumophila (Lp) LPS. For Lp serogroup1, Sofia®FIA and Binax®EIA limits of detection (LOD) were similar; that of BinaxNOW® lower. For all tests the LOD was higher… read more here.
Keywords: antigen tests; urinary antigen; pneumophila lps; legionella pneumophila ... See more keywords
Legionella pneumophila recurrently isolated in a Spanish hospital: Two years of antimicrobial resistance surveillance
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Research"
DOI: 10.1016/j.envres.2018.06.045
Abstract: Objectives: The aim of this study was to monitor the spread, persistence and antibiotic resistance patterns of Legionella spp. strains found in a hospital water distribution system. These environmental studies are intended to help detect… read more here.
Keywords: water; hospital; legionella pneumophila; resistance ... See more keywords
Legionella pneumophila decreases velocity of Acanthamoeba castellanii.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.07.013
Abstract: Acanthamoeba castellanii is a free-living amoeba commonly found in aquatic environment. It feeds on bacteria even if some bacteria resist amoebal digestion. Thus, A. castellanii is described as a Trojan horse able to harbor pathogenic bacteria.… read more here.
Keywords: castellanii; velocity; acanthamoeba castellanii; legionella pneumophila ... See more keywords
Bioassays: The best alternative for conventional methods in detection of Legionella pneumophila.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.09.074
Abstract: Fastidious bacteria are group of bacteria that not only grow slowly but also have complex nutritional needs. In this review, recent progress made on development of biosensing strategies towards quantification of Legionella pneumophila as fastidious… read more here.
Keywords: methods detection; legionella pneumophila; bioassay biosensing; detection legionella ... See more keywords
New system for the detection of Legionella pneumophila in water samples.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.07.013
Abstract: Waterborne pathogens are a global concern for public health worldwide. Despite continuing efforts to maintain water safety, water quality is still affected by deterioration and pollution. Legionella pneumophila colonizes man-made water systems and can infect… read more here.
Keywords: detection; water; water samples; legionella pneumophila ... See more keywords
A Unique Cytoplasmic ATPase Complex Defines the Legionella pneumophila Type IV Secretion Channel
Sign Up to like & getrecommendations! Published in 2018 at "Nature microbiology"
DOI: 10.1038/s41564-018-0165-z
Abstract: Type IV secretion systems (T4SSs) are complex machines used by bacteria to deliver protein and DNA complexes into target host cells1–5. Conserved ATPases are essential for T4SS function, but how they coordinate their activities to… read more here.
Keywords: dot icm; secretion; legionella pneumophila; type secretion ... See more keywords
Population structure of Environmental and Clinical Legionella pneumophila isolates in Catalonia
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24708-1
Abstract: Legionella is the causative agent of Legionnaires’ disease (LD). In Spain, Catalonia is the region with the highest incidence of LD cases. The characterisation of clinical and environmental isolates using molecular epidemiology techniques provides epidemiological… read more here.
Keywords: clinical environmental; environmental clinical; legionella pneumophila; environmental isolates ... See more keywords
A multiplex CRISPR interference tool for virulence gene interrogation in Legionella pneumophila
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-01672-7
Abstract: Catalytically inactive dCas9 imposes transcriptional gene repression by sterically precluding RNA polymerase activity at a given gene to which it was directed by CRISPR (cr)RNAs. This gene silencing technology, known as CRISPR interference (CRISPRi), has… read more here.
Keywords: virulence; gene; crispr interference; legionella pneumophila ... See more keywords
TNF-α response in macrophages depends on clinical Legionella pneumophila isolates genotypes
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2021.2022861
Abstract: ABSTRACT Legionnaires’ Disease (LD) is a severe pneumonia mainly caused in Europe by Legionella pneumophila serogroup 1 (Lp1). Sequence-based typing methods reveal that some sequence types (ST) are overrepresented in clinical samples such as ST1… read more here.
Keywords: isolates induced; legionella pneumophila; tnf secretion; st47 ... See more keywords
Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2149973
Abstract: ABSTRACT Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and… read more here.
Keywords: legionella; histone; legionella pneumophila; deacetylase ... See more keywords