Effect of hybridization on lipophosphoglycan expression in Leishmania major
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11798
Abstract: Leishmania major is the causative agent of cutaneous leishmaniasis. It is one of the most studied Leishmania species not only during vector interaction but also in the vertebrate host. Lipophosphoglycan (LPG) is the Leishmania multifunctional… read more here.
Keywords: hybridization lipophosphoglycan; expression; leishmania; leishmania major ... See more keywords
Chronic Systemic Infection of Mice with Leishmania infantum Leads to Increased Bone Mass
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4733
Abstract: Vector‐borne infections of humans with the protozoan parasite Leishmania (L.) infantum can cause a systemic and potentially lethal disease termed visceral leishmaniasis. In the corresponding mouse model, an intravenous infection with L. infantum leads to… read more here.
Keywords: infantum; bone; infection; leishmania ... See more keywords
Targeting sterol alpha‐14 demethylase of Leishmania donovani to fight against leishmaniasis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29922
Abstract: Leishmaniasis is a neglected tropical disease caused by the protozoan parasite Leishmania. It is endemic in more than 89 different countries worldwide. Sterol alpha‐14 demethylase (LdSDM), a sterol biosynthetic pathway enzyme in Leishmania donovani, plays… read more here.
Keywords: leishmaniasis; sterol alpha; drug; donovani ... See more keywords
Domestic dogs carriers of Leishmania infantum, Leishmania tropica and Crithidia fasciculata as potential reservoirs for human visceral leishmaniasis in northeastern Iran
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.929
Abstract: Abstract Background In recent years, cases of human visceral leishmaniasis (HVL) have been reported in some districts of Golestan Province, northeastern Iran, particularly in rural areas. Recent epidemiological evidence in Leishmania infantum endemic regions of… read more here.
Keywords: human visceral; infantum; domestic dogs; leishmania ... See more keywords
Quantification of Leishmania Parasites in Murine Models of Visceral Infection.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_16
Abstract: Visceral leishmaniasis (VL) is mainly caused by Leishmania donovani (India and East Africa), and Leishmania infantum (Mediterranean Basin and South America) infections. Although murine models of visceral infection lack the clinicopathological aspects of VL in… read more here.
Keywords: models visceral; murine models; infection; quantification leishmania ... See more keywords
Establishment, Maintenance of Phlebotomus spp. in the Laboratory, and Infection with Leishmania spp.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_19
Abstract: Sand fly colonies are of major importance for experimental studies on biology, behavior, vector competence, relationship with Leishmania parasites, and vector control. This chapter is intended to provide methods and techniques used to initiate, establish,… read more here.
Keywords: leishmania spp; spp; maintenance; phlebotomus spp ... See more keywords
A Guide to Next Generation Sequence Analysis of Leishmania Genomes.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_3
Abstract: Next generation sequencing (NGS) technology transformed Leishmania genome studies and became an indispensable tool for Leishmania researchers. Recent Leishmania genomics analyses facilitated the discovery of various genetic diversities including single nucleotide polymorphisms (SNPs), copy number… read more here.
Keywords: ngs analyses; leishmania genomes; leishmania ngs; next generation ... See more keywords
A new multi-epitope peptide vaccine induces immune responses and protection against Leishmania infantum in BALB/c mice
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00640-7
Abstract: Visceral leishmaniasis (VL) is a tropical and subtropical disease which is endemic in more than eighty countries around the world. Leishmania infantum is one of the main causative agents of VL disease. Currently, there is… read more here.
Keywords: immune responses; balb mice; vaccine; leishmania ... See more keywords
Heterogeneity of humoral immune response to Leishmania tropica in an experimental model
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06256-3
Abstract: Humoral (antibody) response is an important part of immunity against pathogens. Despite the clear role of cell-mediated immune response in protection against leishmaniasis, the role of humoral responses is challenging. There is very limited data… read more here.
Keywords: response; immune response; leishmania tropica; leishmania ... See more keywords
In vitro evaluation and in vivo efficacy of nitroimidazole-sulfanyl ethyl derivatives against Leishmania (V.) braziliensis and Leishmania (L.) mexicana.
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology research"
DOI: 10.1007/s00436-021-07266-w
Abstract: The aim of this study was to synthesize several small molecules of the type 5-nitroimidazole-sulfanyl and evaluate biological properties against the main Leishmania species that cause cutaneous leishmaniasis in Venezuela. Final compounds 4-7 were generated… read more here.
Keywords: braziliensis; nitroimidazole sulfanyl; evaluation; leishmania mexicana ... See more keywords
Molecular detection of Leishmania species in northeast of Iran
Sign Up to like & getrecommendations! Published in 2018 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-018-2658-9
Abstract: Two known types of cutaneous leishmaniasis (CL) including zoonotic CL due to Leishmania major and anthroponotic CL due to Leishmania tropica are prevalent in 14 of 22 countries located in the Eastern Mediterranean region including… read more here.
Keywords: northeast iran; molecular detection; leishmania species; species northeast ... See more keywords