Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Lipids"
DOI: 10.1002/lipd.12365
Abstract: Leishmania parasites are the causative agents of visceral or cutaneous leishmaniasis in humans and of canine leishmaniosis. The macrophage is the predilected host cell of Leishmania in which the promastigote stage is transformed into amastigote.… read more here.
Keywords: infectivity towards; towards j774; leishmania infantum; mon ... See more keywords
Study of ocular manifestations and humoral immune response in eyes of dogs with leishmaniasis
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.982
Abstract: Abstract Background Ocular manifestations in dogs with leishmaniasis are frequent and complications in affected tissues can lead to blindness. Immune processes play a very important role in the pathogenesis of ocular inflammation. Therefore, the immunology… read more here.
Keywords: dogs leishmaniasis; ocular manifestations; leishmania infantum; anti leishmania ... See more keywords
In Vitro Infections of Macrophage-Like Cell Lines with Leishmania infantum for Drug Screening.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_14
Abstract: The study of in vitro infections is essential to evaluate distinct aspects of Leishmania biology and also invaluable for more meaningful in vitro screening of promising chemical entities. Macrophage-like cells lines from different origins are… read more here.
Keywords: macrophage like; cell lines; vitro infections; biology ... See more keywords
Thiosemicarbazone and thiazole: in vitro evaluation of leishmanicidal and ultrastructural activity on Leishmania infantum
Sign Up to like & getrecommendations! Published in 2020 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-020-02619-z
Abstract: Leishmaniasis is a much-neglected tropical disease, especially in developing countries. Visceral Leishmaniasis (VL) is the most severe form of this infection caused by Leishmania infantum specie. It affects the splenic and hepatic systems and, when… read more here.
Keywords: thiosemicarbazone thiazole; evaluation; activity; leishmania infantum ... See more keywords
A new multi-epitope peptide vaccine induces immune responses and protection against Leishmania infantum in BALB/c mice
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00640-7
Abstract: Visceral leishmaniasis (VL) is a tropical and subtropical disease which is endemic in more than eighty countries around the world. Leishmania infantum is one of the main causative agents of VL disease. Currently, there is… read more here.
Keywords: immune responses; balb mice; vaccine; leishmania ... See more keywords
Canine Leishmania infantum infection: an imported case in UK after staying in the Canary Islands
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology Research"
DOI: 10.1007/s00436-017-5681-x
Abstract: Leishmaniosis is reported in the Iberian Peninsula and the Balearic Islands, but the Canary Islands are deemed free. In the present communication, we report a clinical leishmaniosis due to Leishmania infantum in a dog that… read more here.
Keywords: infantum; case; canary islands; canine leishmania ... See more keywords
The vector competence of Phlebotomus perniciosus for Leishmania infantum zymodemes of Tunisia
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology Research"
DOI: 10.1007/s00436-018-5939-y
Abstract: Experimental infections of Phlebotomus (L.) perniciosus from a colony established in Madrid (Spain) carried out with the Leishmania (L.) infantum zymodemes MON-1, MON-24, and MON-80 isolated in Tunisia are reported here. Laboratory-reared female sand flies… read more here.
Keywords: infantum; sand; phlebotomus perniciosus; infantum zymodemes ... See more keywords
Population structures of Leishmania infantum and Leishmania tropica the causative agents of kala-azar in Southwest Iran
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology Research"
DOI: 10.1007/s00436-018-6041-1
Abstract: Visceral leishmaniasis (VL) is endemic in Iran and is caused predominantly by Leishmania infantum, but L. tropica is emerging as an important cause. We studied the intra-species population structure of Leishmania spp. causing VL in… read more here.
Keywords: southwest iran; tropica; population structures; leishmania infantum ... See more keywords
The impact of canine leishmaniosis vaccination with CaniLeish® in Leishmania infantum infection seroprevalence studies.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2019.105259
Abstract: Effective vaccines against Leishmania parasites are a goal for the scientific community working with both canine and human leishmaniosis. However, possible side effects of vaccination should also be considered and evaluated, preferably before vaccine licensing… read more here.
Keywords: infection; leishmaniosis; canine leishmaniosis; vaccination ... See more keywords
Seasonal dynamics of phlebotomine sand flies and autochthonous transmission of Leishmania infantum in high-altitude ecosystems in southern Spain.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105749
Abstract: Leishmaniasis is a vector-borne disease transmitted by sand flies. A dozen species have been involved in the transmission of Leishmania infantum in the Mediterranean region. Climate change may alter sand fly distribution at particular altitudes… read more here.
Keywords: sand; southern spain; sand fly; sand flies ... See more keywords
A comparative approach on the activation of the three complement system pathways in different hosts of Visceral Leishmaniasis after stimulation with Leishmania infantum.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104061
Abstract: Visceral Leishmaniasis is an infectious disease that affects mainly humans and dogs, with the latter being important reservoirs of the parasite. Conversely, cats are naturally resistant. The immune system can offer important explanation to this… read more here.
Keywords: system; complement system; visceral leishmaniasis; complement ... See more keywords