The role of monocytes/macrophages in Leishmania infection: a glance at the human response.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105456
Abstract: Leishmania are obligate intracellular parasites of mononuclear phagocytes transmitted by Phlebotomine sandflies. Monocytes are one of the main cell types recruited to the site of the bite having an important role in the defense against Leishmania… read more here.
Keywords: monocytes macrophages; macrophages leishmania; infection; role monocytes ... See more keywords
Virus-like Particle Display of the α-Gal Carbohydrate for Vaccination against Leishmania Infection
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DOI: 10.1021/acscentsci.7b00311
Abstract: Secreted and surface-displayed carbohydrates are essential for virulence and viability of many parasites, including for immune system evasion. We have identified the α-Gal trisaccharide epitope on the surface of the protozoan parasites Leishmania infantum and… read more here.
Keywords: like particle; virus like; infection; leishmania infection ... See more keywords
Drugs and nanoformulations for the management of Leishmania infection: a patent and literature review (2015-2022)
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DOI: 10.1080/13543776.2023.2201431
Abstract: ABSTRACT Introduction Leishmaniasis is an important disease caused by parasites of the Leishmania. Due to the urgent need for financial incentives and research and development of new anti-Leishmania, a point that stands out is the… read more here.
Keywords: drugs nanoformulations; 2015 2022; leishmania infection; treatment ... See more keywords
Metamorphosis of neutrophil transcriptional programme during Leishmania infection
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DOI: 10.1111/pim.12922
Abstract: The role of neutrophils in the course of Leishmania infection remains controversial, displaying tremendous variability depending on the species of parasite, stage of infection, host genetic background, and methodological discrepancies among studies. Although neutrophils have… read more here.
Keywords: transcriptional programme; infection; leishmania infection; metamorphosis neutrophil ... See more keywords
Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection
Sign Up to like & getrecommendations! Published in 2017 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-017-2318-8
Abstract: BackgroundLeishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test is warranted for on-time diagnosis and… read more here.
Keywords: diagnosis; leishmania infection; amplification; assessment cure ... See more keywords
Longitudinal evaluation of asymptomatic Leishmania infection in HIV-infected individuals in North-West Ethiopia: A pilot study
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007765
Abstract: Background In endemic regions, asymptomatic Leishmania infection is common. In HIV patients, detection of asymptomatic Leishmania infection could potentially identify those at risk of visceral leishmaniasis (VL). However, data on the prevalence, incidence, and determinants… read more here.
Keywords: leishmania; infection; asymptomatic leishmania; leishmania infection ... See more keywords
Leishmania infection in blood donors: A new challenge in leishmaniasis transmission?
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DOI: 10.1371/journal.pone.0198199
Abstract: Transfusion-transmitted leishmaniasis has been a concern in regions endemic for the disease. Whether immediate or delayed, the risks posed by this mode of transmission call for careful assessment. The purpose of this study was to… read more here.
Keywords: transmission; infection blood; leishmania infection; leishmaniasis ... See more keywords
Humoral response in Leishmaniasis
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DOI: 10.3389/fcimb.2022.1063291
Abstract: Leishmaniasis presents different types of clinical manifestations that can be divided into cutaneous leishmaniasis and visceral leishmaniasis. The host’s immune system, associated with genetic and nutritional factors, is strongly involved in the evolution of the… read more here.
Keywords: infection; response leishmaniasis; leishmania infection; microbiology ... See more keywords
Interleukin-27 Functional Duality Balances Leishmania Infectivity and Pathogenesis
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DOI: 10.3389/fimmu.2020.01573
Abstract: IL-27 is a cytokine that exerts diverse effects on the cells of innate and adaptive immune systems. Chiefly expressed in macrophages and dendritic cells during the early phase of Leishmania infection, IL-27 contributes to the… read more here.
Keywords: duality; interleukin functional; duality balances; functional duality ... See more keywords
Arginine and Polyamines Fate in Leishmania Infection
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02682
Abstract: Leishmania is a protozoan parasite that alternates its life cycle between the sand fly and the mammalian host macrophages, involving several environmental changes. The parasite responds to these changes by promoting a rapid metabolic adaptation… read more here.
Keywords: fate leishmania; arginine polyamines; infection; polyamines fate ... See more keywords
The Dangerous Liaisons in the Oxidative Stress Response to Leishmania Infection
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DOI: 10.3390/pathogens11040409
Abstract: Leishmania parasites preferentially invade macrophages, the professional phagocytic cells, at the site of infection. Macrophages play conflicting roles in Leishmania infection either by the destruction of internalized parasites or by providing a safe shelter for… read more here.
Keywords: response; oxidative stress; leishmania infection; infection ... See more keywords