Redox biology of Leishmania and macrophage targeted nanoparticles for therapy.
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DOI: 10.2217/nnm-2017-0049
Abstract: Intramacrophage parasite 'Leishmania' has developed various mechanisms for proficient uptake into macrophages and phagosome regulation to avoid macrophage's oxidative burst induced by peroxide, hydroxyl radical, hypochlorous acid and peroxynitrite production. One major barrier for impairing… read more here.
Keywords: targeted nanoparticles; leishmania macrophage; drug; biology ... See more keywords