Molecular detection of Leishmania species in northeast of Iran
Sign Up to like & getrecommendations! Published in 2018 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-018-2658-9
Abstract: Two known types of cutaneous leishmaniasis (CL) including zoonotic CL due to Leishmania major and anthroponotic CL due to Leishmania tropica are prevalent in 14 of 22 countries located in the Eastern Mediterranean region including… read more here.
Keywords: northeast iran; molecular detection; leishmania species; species northeast ... See more keywords
Prevalence of Leishmania species in rodents: A systematic review and meta-analysis in Iran.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.04.022
Abstract: Leishmaniasis are diverse group of diseases caused by numerous species of genus Leishmania. Herein we have contrived a systematic review and meta-analysis on the prevalence of Leishmania species in rodents of Iran. For this purpose,… read more here.
Keywords: leishmania species; prevalence leishmania; prevalence; meta analysis ... See more keywords
New epidemiological pattern of cutaneous leishmaniasis in two pre-Saharan arid provinces, southern Morocco.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.05.016
Abstract: Three Leishmania species are responsible of cutaneous leishmaniasis (CL) in Morocco. Zoonotic CL due to Leishmania major and Leishmania infantum, the first is known as established in the eastern arid regions, whereas the latter evolves… read more here.
Keywords: leishmania species; pre saharan; epidemiological pattern; cutaneous leishmaniasis ... See more keywords
A rapid high-resolution melting method for differentiation of Leishmania species targeting lack gene.
Sign Up to like & getrecommendations! Published in 2018 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.10.016
Abstract: OBJECTIVES The aim of this research is to verify that if lack gene can be used for differentiation of Leishmania under HRM assay. METHODS Two specific primers were designed targeting polymorphic sites on the lack… read more here.
Keywords: gene; differentiation leishmania; leishmania species; lack gene ... See more keywords
Duplex qPCR for Leishmania species identification using lesion imprint on filter paper.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2020.108019
Abstract: BACKGROUND American cutaneous leishmaniasis (ACL) is caused by different Leishmania parasites, which stimulate and direct the immune response against the infection. OBJECTIVE To evaluate the TaqMan probe technology applicability to diagnose and identifying of Leishmania… read more here.
Keywords: lesion imprint; leishmania species; duplex qpcr; lesion ... See more keywords
The role of metalloproteases in Leishmania species infection in the New World: a systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology"
DOI: 10.1017/s0031182018000367
Abstract: Abstract This is a systematic review on the role of metalloproteases in the pathogenicity of the American tegumentary leishmaniasis (ATL) caused by New World Leishmania species. The review followed the PRISMA method, searching for articles… read more here.
Keywords: role metalloproteases; systematic review; new world; leishmania species ... See more keywords
Proteomic Analysis of the Promastigote Secretome of Seven Leishmania Species.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00244
Abstract: Leishmaniasis is one of the most impactful parasitic diseases worldwide, endangering the lives of 1 billion people every year. There are 20 different species of Leishmania able to infect humans, causing cutaneous (CL), visceral (VL),… read more here.
Keywords: promastigote secretome; analysis promastigote; leishmania species; seven leishmania ... See more keywords
An interactive database of Leishmania species distribution in the Americas
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Data"
DOI: 10.1038/s41597-020-0451-5
Abstract: The Americas have an elevated number of leishmaniasis cases (accounting for two-thirds of the worldwide disease burden) and circulating Leishmania species, and are therefore of interest in terms of epidemiological surveillance. Here, we present a… read more here.
Keywords: leishmania; leishmania species; database; type ... See more keywords
The role of heparan sulfate in host macrophage infection by Leishmania species.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Society transactions"
DOI: 10.1042/bst20170398
Abstract: The leishmaniases are a group of neglected tropical diseases caused by parasites from the Leishmania genus. More than 20 Leishmania species are responsible for human disease, causing a broad spectrum of symptoms ranging from cutaneous… read more here.
Keywords: infection; leishmania species; role; host ... See more keywords
Distribution, treatment outcome and genetic diversity of Leishmania species in military personnel from Colombia with cutaneous leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-020-05529-y
Abstract: Background Leishmaniasis is one of the most important infectious diseases affecting the Colombian National Army due to the high number of reported cases and exposure throughout military operations in endemic areas. The main aim of… read more here.
Keywords: leishmaniasis; military personnel; genetic diversity; leishmania species ... See more keywords
Kaurane-Type Diterpenoids as Potential Inhibitors of Dihydrofolate Reductase-Thymidylate Synthase in New World Leishmania Species
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12040663
Abstract: The bifunctional enzyme Dihydrofolate reductase-thymidylate synthase (DHFR-TS) plays a crucial role in the survival of the Leishmania parasite, as folates are essential cofactors for purine and pyrimidine nucleotide biosynthesis. However, DHFR inhibitors are largely ineffective… read more here.
Keywords: thymidylate synthase; reductase thymidylate; new world; reductase ... See more keywords