Heterogeneity of humoral immune response to Leishmania tropica in an experimental model
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06256-3
Abstract: Humoral (antibody) response is an important part of immunity against pathogens. Despite the clear role of cell-mediated immune response in protection against leishmaniasis, the role of humoral responses is challenging. There is very limited data… read more here.
Keywords: response; immune response; leishmania tropica; leishmania ... See more keywords
The impact of refugees on leishmaniasis in Turkey: a new Syrian/Turkish Leishmania tropica population structure described by multilocus microsatellite typing (MLMT)
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06392-w
Abstract: Turkey is one of the leishmaniasis endemic countries, and according to the recent reports, more than 45% of the cases were reported from the Southeastern part of Turkey. The disease is endemic in Syria with… read more here.
Keywords: syrian turkish; present study; population structure; structure ... See more keywords
Leishmania tropica infected human lesions: Whole genome transcription profiling.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.08.016
Abstract: Leishmania (L.) tropica is the main causative agent of anthroponotic cutaneous leishmaniasis (CL) in Iran. Defining the host inflammatory response in the L. tropica lesions are crucial for the development of new treatment modalities. High-throughput… read more here.
Keywords: transcription; tropica; infected human; tropica infected ... See more keywords
Possible introduction of Leishmania tropica to urban areas determined by epidemiological and clinical profiles of patients with cutaneous leishmaniasis in Casablanca (Morocco)
Sign Up to like & getrecommendations! Published in 2020 at "Parasite Epidemiology and Control"
DOI: 10.1016/j.parepi.2019.e00129
Abstract: Leishmaniases are a group of infectious diseases caused by protozoan Leishmania parasites and are transmitted by the bites of infected phlebotomine sandflies. The heterogeneity of these diseases is influenced by both parasitic properties and host… read more here.
Keywords: urban areas; epidemiological clinical; morocco; cutaneous leishmaniasis ... See more keywords
Molecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-72671-7
Abstract: Anthroponotic cutaneous leishmaniasis (CL) caused by Leishmania tropica (L. tropica) represents a public health challenge in several resource poor settings. We herein employed a systems analysis approach to study molecular signatures of CL caused by… read more here.
Keywords: tropica; lesions patients; molecular signatures; cutaneous leishmaniasis ... See more keywords
Treating pediatric cutaneous Leishmania tropica with systemic liposomal amphotericin B: A retrospective, single-center study.
Sign Up to like & getrecommendations! Published in 2021 at "Dermatologic therapy"
DOI: 10.1111/dth.15185
Abstract: BACKGROUND Leishmania tropica (L. tropica) is associated with high morbidity and low response rate to therapy, especially in pediatric patients. Intravenous (IV) liposomal amphotericin B (LAmB) has been used off-label as a treatment for L.… read more here.
Keywords: response; tropica; liposomal amphotericin; center ... See more keywords
Temperature Effects on the Activity of Vectors for Leishmania tropica along Rocky Habitat Gradients in the Eastern Mediterranean
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Vector Ecology"
DOI: 10.1111/jvec.12304
Abstract: ABSTRACT: Cutaneous leishmaniasis caused by Leishmania tropica, transmitted by Phlebotomus sergenti and Phlebotomus arabicus, has been detected in Israel. This research strives to identify the complexity of temperature effects on vectors of L. tropica and… read more here.
Keywords: temperature; activity vectors; effects activity; temperature effects ... See more keywords
Genetic diversity of Leishmania tropica in Morocco: does the dominance of one haplotype signify its fitness in both predominantly anthropophilic Phlebotomus sergenti and human beings?
Sign Up to like & getrecommendations! Published in 2019 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.13031
Abstract: In Morocco, cutaneous leishmaniasis (CL) caused by Leishmania tropica is endemic to locations where the predominantly anthropophilic blood-feeding Phlebotomus sergenti and humans co-perpetuate. The objective of this study was to explore whether the range of… read more here.
Keywords: diversity; genetic diversity; tropica; haplotype ... See more keywords
Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008684
Abstract: Leishmania tropica is one of the main causative agents of cutaneous leishmaniasis (CL). Population structures of L. tropica appear to be genetically highly diverse. However, the relationship between L. tropica strains genomic diversity, protein coding… read more here.
Keywords: protein coding; tropica; population; leishmania tropica ... See more keywords
HAS 1: A natural product from soil-isolated Streptomyces species with potent activity against cutaneous leishmaniasis caused by Leishmania tropica
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1023114
Abstract: Cutaneous Leishmaniasis (CL) is a neglected tropical disease, classified by the World Health Organization (WHO) as one of the most unrestrained diseases. The Syrian war and the significant displacement of refugees aggravated the spread of… read more here.
Keywords: leishmania; soil; leishmania tropica; cutaneous leishmaniasis ... See more keywords
Independent Circulation of Leishmania major and Leishmania tropica in Their Respective Sandfly Vectors for Transmission of Zoonotic and Chronic Cutaneous Leishmaniasis Co-Existing in a Mixed Focus of Central Tunisia
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11080855
Abstract: Zoonotic cutaneous leishmaniasis (ZCL) and chronic cutaneous leishmaniasis (CCL) are known to overlap in Central Tunisia. Sandflies were collected using sticky traps and CDC light-traps set in rodent burrows at the ecotones surrounding the village,… read more here.
Keywords: mixed focus; sandfly; leishmania; leishmania tropica ... See more keywords