Incidence of Endemic Human Cutaneous Leishmaniasis in the United States
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.2133
Abstract: Importance Leishmaniasis is recognized as an endemic human disease in Africa, the Middle East, Asia, and South America. Yet despite case reports of endemic human leishmaniasis in the United States, and well-documented occurrences of disease… read more here.
Keywords: leishmaniasis; leishmaniasis united; disease; endemic human ... See more keywords
Membrane‐acting biomimetic peptoids against visceral leishmaniasis
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13562
Abstract: Visceral leishmaniasis (VL) is among the most neglected tropical diseases in the world. Drug cell permeability is essential for killing the intracellular residing parasites responsible for VL, making cell‐permeating peptides a logical choice to address… read more here.
Keywords: visceral leishmaniasis; membrane acting; acting biomimetic; peptoids visceral ... See more keywords
Repurposing of FDA-approved drugs as inhibitors of sterol C-24 methyltransferase of Leishmania donovani to fight against leishmaniasis.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21820
Abstract: Leishmaniasis is a vector-borne disease caused by around 20 species of Leishmania. The main clinical forms of leishmaniasis are cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL). VL is caused by Leishmania infantum in Central and… read more here.
Keywords: sterol methyltransferase; leishmaniasis; drug; donovani ... See more keywords
Targeting sterol alpha‐14 demethylase of Leishmania donovani to fight against leishmaniasis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29922
Abstract: Leishmaniasis is a neglected tropical disease caused by the protozoan parasite Leishmania. It is endemic in more than 89 different countries worldwide. Sterol alpha‐14 demethylase (LdSDM), a sterol biosynthetic pathway enzyme in Leishmania donovani, plays… read more here.
Keywords: leishmaniasis; sterol alpha; drug; donovani ... See more keywords
Microscopic and molecular evidence in support of rodent as a reservoir for dissemination of Leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23462
Abstract: Leishmaniasis is a worldwide public health problem and vector‐borne disease. It is caused by a diverse group of protozoan parasites that belong to the genus Leishmania and transmitted to humans through a bite of an… read more here.
Keywords: microscopic molecular; leishmaniasis; microscopy; molecular evidence ... See more keywords
Domestic dogs carriers of Leishmania infantum, Leishmania tropica and Crithidia fasciculata as potential reservoirs for human visceral leishmaniasis in northeastern Iran
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.929
Abstract: Abstract Background In recent years, cases of human visceral leishmaniasis (HVL) have been reported in some districts of Golestan Province, northeastern Iran, particularly in rural areas. Recent epidemiological evidence in Leishmania infantum endemic regions of… read more here.
Keywords: human visceral; infantum; domestic dogs; leishmania ... See more keywords
Experimental Cutaneous Leishmaniasis: Mouse Models for Resolution of Inflammation Versus Chronicity of Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_18
Abstract: Experimental cutaneous leishmaniasis of mice is a valuable model to study the immune response to the protozoan pathogen Leishmania and to define mechanisms of parasite control and resolution of inflammation as well as of parasite… read more here.
Keywords: experimental cutaneous; leishmaniasis; chronicity disease; cutaneous leishmaniasis ... See more keywords
Leishmaniasis immunopathology—impact on design and use of vaccines, diagnostics and drugs
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-020-00788-y
Abstract: Leishmaniasis is a disease complex caused by 20 species of protozoan parasites belonging to the genus Leishmania . In humans, it has two main clinical forms, visceral leishmaniasis (VL) and cutaneous or tegumentary leishmaniasis (CL),… read more here.
Keywords: immunopathology impact; leishmaniasis; leishmaniasis immunopathology; vaccines diagnostics ... See more keywords
First identification of L. major in a dog in an endemic area of human cutaneous leishmaniasis in Iraq: molecular and phylogenetic studies
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology Research"
DOI: 10.1007/s00436-017-5704-7
Abstract: Canine leishmaniasis (CanL) caused by Leishmania infantum (L. infantum) is considered as a zoonotic disease and within the last few decades, studies have identified the parasite as a major causative agent of human visceral leishmaniasis.… read more here.
Keywords: iraq molecular; leishmaniasis; area human; area ... See more keywords
Susceptibility to leishmaniasis is affected by host SLC11A1 gene polymorphisms: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06374-y
Abstract: Leishmaniases are cutaneous, mucocutaneous, and visceral diseases affecting humans and domesticated animals mostly in the tropical and subtropical areas of the planet. Host genetics have been widely investigated for their role in developing various infectious… read more here.
Keywords: slc11a1 gene; leishmaniasis; susceptibility; meta analysis ... See more keywords
Transmission of leishmaniasis from human to other vertebrates: a rapid zooanthroponotic evolution
Sign Up to like & getrecommendations! Published in 2019 at "International Microbiology"
DOI: 10.1007/s10123-019-00055-7
Abstract: Research regarding zoonotic diseases often focuses on those diseases that are transferred from animals to humans. However, humans are also transmitting pathogens to animals but research on this topic is not given priority and importance.… read more here.
Keywords: leishmaniasis human; leishmaniasis; human vertebrates; transmission leishmaniasis ... See more keywords