Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease
Sign Up to like & getrecommendations! Published in 2019 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2019.05.002
Abstract: Visceral leishmaniasis (VL) and Chagas disease (CD) are caused by kinetoplastid parasites that affect millions of people worldwide and impart a heavy burden against human health. Due to the partial efficacy and toxicity-related limitations of… read more here.
Keywords: starting points; drug; leishmaniasis chagas; drug discovery ... See more keywords
Hybrid Molecules: Promising Compounds for the Development of New Treatments Against Leishmaniasis and Chagas Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867325666180309111428
Abstract: Leishmaniasis and Chagas disease are endemic pathologies in tropical countries. These cause high morbidity and a public health problem. Current chemotherapies are based on conventional drugs with variable efficacy and toxicity related with the length… read more here.
Keywords: hybrid molecules; leishmaniasis; leishmaniasis chagas; new treatments ... See more keywords
Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1000972
Abstract: Nanotechnology is revolutionizing many sectors of science, from food preservation to healthcare to energy applications. Since 1995, when the first nanomedicines started being commercialized, drug developers have relied on nanotechnology to improve the pharmacokinetic properties… read more here.
Keywords: neglected tropical; chagas disease; nanotechnology; leishmaniasis chagas ... See more keywords