Novel prenyloxy chalcones as potential leishmanicidal and trypanocidal agents: Design, synthesis and evaluation.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.02.028
Abstract: The available drugs for treating Leishmaniasis and American trypanosomiasis have high toxicity and multiple side effects, among other problems. More effective and less toxic treatments are urgently needed. A series of chalcones that contained a… read more here.
Keywords: trypanocidal; chalcones potential; cruzi; prenyloxy chalcones ... See more keywords
Leishmanicidal and trypanocidal potential of the essential oil of Psidium myrsinites DC.
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DOI: 10.1080/14786419.2020.1844688
Abstract: Neglected tropical diseases (NTDs) are a group of pathologies caused by infectious agents or parasites, including the protozoa Leishmania sp. and Trypanosoma cruzi, which cause leishmaniasis and Chagas disease, respectively. The complications of the treatment… read more here.
Keywords: essential oil; psidium myrsinites; oil psidium; leishmanicidal trypanocidal ... See more keywords
Evaluation of the in vitro schistosomicidal, leishmanicidal, and trypanocidal activities of the capsaicin metabolite, Capsicum frutescens, and Capsicum baccatum extracts and of their analysis of the main constituents by HPLC/UV and CG/MS.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2023.2187793
Abstract: Neglected tropical diseases are significant causes of death and temporary or permanent disability for millions living in developing countries. Unfortunately, there is no effective treatment for these diseases. Thus, this work aimed to conduct a… read more here.
Keywords: frutescens capsicum; capsicum frutescens; leishmanicidal trypanocidal; trypanocidal activities ... See more keywords