Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-48394-y
Abstract: Genome-wide association studies (GWAS) have become well-powered to detect loci associated with telomere length. However, no prior work has validated genes nominated by GWAS to examine their role in telomere length regulation. We conducted a… read more here.
Keywords: association; length regulation; telomere length; association signals ... See more keywords
Ciliary length regulation by intraflagellar transport in zebrafish
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.1101/2024.01.16.575975
Abstract: How cells regulate the size of their organelles remains a fundamental question in cell biology. Cilia, with their simple structure and surface localization, provide an ideal model for investigating organelle size control. However, most studies… read more here.
Keywords: length regulation; intraflagellar transport; size; ift ... See more keywords
Limited Resources Induce Bistability in Microtubule Length Regulation.
Sign Up to like & getrecommendations! Published in 2018 at "Physical review letters"
DOI: 10.1103/physrevlett.120.148101
Abstract: The availability of protein is an important factor for the determination of the size of the mitotic spindle. Involved in spindle-size regulation is kinesin-8, a molecular motor and microtubule (MT) depolymerase, which is known to… read more here.
Keywords: microtubule; limited resources; length regulation; resources induce ... See more keywords