Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA.
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DOI: 10.1007/s00439-021-02408-7
Abstract: Spinal muscular atrophy (SMA) is a debilitating neurodegenerative pediatric disease characterized by low levels of the survival motor protein (SMN). Humans have two SMN genes that produce identical SMN proteins, but they differ at a… read more here.
Keywords: length; full length; heat; protein ... See more keywords