A genetic risk score using human chromosomal-scale length variation can predict schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-97983-0
Abstract: Studies indicate that schizophrenia has a genetic component, however it cannot be isolated to a single gene. We aimed to determine how well one could predict that a person will develop schizophrenia based on their… read more here.
Keywords: schizophrenia; scale length; risk score; chromosomal scale ... See more keywords
Adaptive protein evolution through length variation of short tandem repeats in Arabidopsis
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add6960
Abstract: Intrinsically disordered protein regions are of high importance for biotic and abiotic stress responses in plants. Tracts of identical amino acids accumulate in these regions and can vary in length over generations because of expansions… read more here.
Keywords: length variation; tandem repeats; short tandem; length ... See more keywords
miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR.
Sign Up to like & getrecommendations! Published in 2019 at "RNA"
DOI: 10.1261/rna.069047.118
Abstract: Most microRNAs (miRNAs) are expressed as a mix of length isoforms (referred to as isomiRs). IsomiR stoichiometry can be differentially impacted upon cell stimulation, as recently evidenced by our group in the context of immune… read more here.
Keywords: stimulation; macrophage stimulation; length variation; mirna length ... See more keywords
Telomere Length Variation in Model Bryophytes
Sign Up to like & getrecommendations! Published in 2024 at "Plants"
DOI: 10.3390/plants13030387
Abstract: The ends of linear chromosomes of most eukaryotes consist of protein-bound DNA arrays called telomeres, which play essential roles in protecting genome integrity. Despite general evolutionary conservation in function, telomeric DNA is known to drastically… read more here.
Keywords: variation model; length variation; model bryophytes; model ... See more keywords