Requirement for Crk and CrkL during postnatal lens development.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.108
Abstract: The Crk and CrkL adaptor proteins have SH2 and SH3 domains and play essential overlapping, as well as distinct, roles in many biological processes, ranging from cell structure and motility to proliferation. Conditional ablation of… read more here.
Keywords: lens development; crkl; postnatal lens; crk crkl ... See more keywords
Mechanisms of organelle elimination for lens development and differentiation.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108682
Abstract: A hallmark feature of lens development and differentiation is the complete elimination of organelles from the center of the eye lens. A long unanswered question in lens biology is what are the mechanisms that control… read more here.
Keywords: lens development; mechanisms organelle; differentiation; elimination ... See more keywords
Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10615-4
Abstract: Lens development involves a complex and highly orchestrated regulatory program. Here, we investigate the transcriptomic alterations and splicing events during mouse lens formation using RNA-seq data from multiple developmental stages, and construct a molecular portrait… read more here.
Keywords: transcriptome analysis; lens development; analysis; novel transcripts ... See more keywords
Beyond the Channels: Adhesion Functions of Aquaporin 0 and Connexin 50 in Lens Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.866980
Abstract: Lens, an avascular tissue involved in light transmission, generates an internal microcirculatory system to promote ion and fluid circulation, thus providing nutrients to internal lens cells and excreting the waste. This unique system makes up… read more here.
Keywords: cell adhesion; lens development; development transparency; aqp0 cx50 ... See more keywords