Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration
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DOI: 10.1016/j.neulet.2018.10.038
Abstract: Converging evidence demonstrates an important role for gangliosides in brain function and neurodegenerative diseases. Exogenous GM1 is broadly neuroprotective, including in rodent, feline, and primate models of Parkinson's disease, and has shown positive effects in… read more here.
Keywords: gd3 synthase; lentiviral mediated; motor; mptp induced ... See more keywords