Gene therapy by lentivirus‐mediated RNA interference targeting extracellular‐regulated kinase alleviates neuropathic pain in vivo
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DOI: 10.1002/jcb.28090
Abstract: Neuropathic pain is an abnormal pain, which is related to the activation of extracellular‐regulated kinase (ERK) signaling. This study was to investigate the effects of ERK knockdown via lentivirus‐mediated RNA interference on allodynia in rats… read more here.
Keywords: lentivirus mediated; extracellular regulated; mediated rna; regulated kinase ... See more keywords
Expression of Concern to: Lentivirus mediated silencing of Ubiquitin Specific Peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Biological Research"
DOI: 10.1186/s40659-018-0170-y
Abstract: Concerns have been raised about this article [1] relating to the appropriateness of the use of the shRNA (5′-GCGGAGGGTTTGAAAGAATATCTCGAGATATTCTTTCAAACCCTCCGCTTTTTT-3′) as a non-targeting control and similarities in text and formatting with other published articles. This is… read more here.
Keywords: mediated silencing; lentivirus mediated; ubiquitin specific; concern lentivirus ... See more keywords
Lentivirus-mediated RNA interference inhibits the tumorigenicity of cluster of differentiation 44+ tumor cells in hypopharyngeal cancer
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DOI: 10.3892/ol.2017.6838
Abstract: The present study aimed to investigate whether the inhibition of cluster of differentiation (CD)44 expression reduces the tumorigenicity of CD44+ cancer stem cells in hypopharyngeal cancer. To assess this, effective recombinant CD44 short hairpin RNA-expressing… read more here.
Keywords: cells hypopharyngeal; lentivirus mediated; group; hypopharyngeal cancer ... See more keywords