Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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DOI: 10.3389/fbioe.2022.960192
Abstract: Type VI CRISPR effector Cas13d from Ruminococcus flavefaciens XPD3002 (RfxCas13d) is an RNA-guided RNA endonuclease. RfxCas13d has been harnessed to knockdown gene expression with high specificity in various systems including mammalian cells. While inducible knockdown… read more here.
Keywords: cas13d; efficient reversible; lentivirus vector; vector ... See more keywords