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Expression of LEP, LEPR and PGC1A genes is altered in peripheral blood mononuclear cells of patients with relapsing-remitting multiple sclerosis

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Published in 2020 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2019.577090

Abstract: Leptin (LEP) may contribute to the pathogenesis of multiple sclerosis (MS) by its immunomodulatory, proinflammatory and prooxidant effects. Therefore, plasma LEP levels and mRNA expression of five genes related to the LEP signaling pathway (LEP,… read more here.

Keywords: lepr pgc1a; relapsing remitting; pgc1a; multiple sclerosis ... See more keywords