Leptin polymorphism rs3828942: risk for anxiety disorders?
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-019-01051-8
Abstract: Leptin is an anorexigenic hormone well recognized by its role in mediating energy homeostasis. Recently, leptin has been associated with psychiatric disorders and interestingly, leptin treatment has shown antidepressant and anxiolytic effects. We examined the… read more here.
Keywords: rs3828942; anxiety; leptin levels; anxiety disorders ... See more keywords
Insights into the Mechanisms That May Clarify Obesity as a Risk Factor for Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-018-0827-5
Abstract: Purpose of ReviewThe proportion to which genetic and environmental factors contribute to the etiology of multiple sclerosis (MS) is still incompletely understood. An interesting association between MS etiology and obesity has recently been shown although… read more here.
Keywords: etiology; leptin levels; multiple sclerosis; obese individuals ... See more keywords
Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-018-0845-9
Abstract: PurposeLeptin is an adipokine which regulates appetite and energy balance through a mechanism partially mediated by neurotensin (NT) in central nervous system. Besides acting as a neurotransmitter, NT is expressed in human intestine where it… read more here.
Keywords: leptin; leptin levels; type diabetes; diabetes mellitus ... See more keywords
In utero exposure to di(2-ethylhexyl)phthalate suppresses blood glucose and leptin levels in the offspring of wild-type mice.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology"
DOI: 10.1016/j.tox.2019.01.008
Abstract: Exposure of pregnant mice to di(2-ethylhexyl)phthalate (DEHP) induces maternal lipid malnutrition and decreases the number of live fetuses/pups. In this study, we aimed to clarify the relationship between maternal lipid malnutrition and the nutritional status… read more here.
Keywords: dehp; exposure; leptin levels; mice ... See more keywords
Leptin at birth and at age 7 in relation to appetitive behaviors at age 7 and age 10
Sign Up to like & getrecommendations! Published in 2020 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2020.104842
Abstract: Leptin contributes to the control of food intake and energy balance. However, its association with appetitive behaviors during childhood is not well understood. We aimed to investigate the association between leptin, assessed at birth and… read more here.
Keywords: higher leptin; age; appetitive behaviors; leptin levels ... See more keywords
Relationships between circulating 25(OH) vitamin D, leptin levels and visceral adipose tissue volume: results from a 1-year lifestyle intervention program in men with visceral obesity
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Obesity"
DOI: 10.1038/s41366-019-0347-7
Abstract: Background/ObjectivesObesity has been associated with elevated leptinemia and vitamin D deficiency. To date, whether there is an association between vitamin D and leptin levels independent from adiposity remains uncertain. Our objective was to investigate the… read more here.
Keywords: year; leptin levels; adipose tissue; vitamin ... See more keywords
Origins of Neonatal Leptin Deficiency in Preterm Infants
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric research"
DOI: 10.1038/s41390-019-0359-y
Abstract: BackgroundCord blood leptin increases with advancing gestation. Preterm delivery leads to premature separation from the maternal and placental leptin source predisposing infants to postnatal leptin deficiency, but this has not been fully described.MethodBlood leptin levels… read more here.
Keywords: leptin deficiency; preterm; leptin; leptin levels ... See more keywords
Lower SHBG level is associated with higher leptin and lower adiponectin levels as well as metabolic syndrome, independent of testosterone
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03078-0
Abstract: In addition to testosterone (T), the emerging role of sex hormone-binding globulin (SHBG) in pathogenesis of metabolic syndrome (MetS) has been noted recently. However, reports of associations with serum adipocytokine levels are still limited. Therefore,… read more here.
Keywords: shbg; leptin levels; testosterone; adiponectin ... See more keywords
Metreleptin for the treatment of lipodystrophy: leading the way among novel therapeutics for this unmet clinical need
Sign Up to like & getrecommendations! Published in 2022 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2022.2059974
Abstract: Leptin, discovered in 1994, is the prototype adipokine that fundamentally advanced our knowledge of the pathophysiology of adipose tissue, opening new avenues in the diagnosis and treatment of metabolic diseases. Until then, the function of… read more here.
Keywords: leptin; leptin levels; energy; adipose tissue ... See more keywords
The relationships between leptin levels in maternal serum and breast milk of mothers and term infants
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine"
DOI: 10.1080/07853890.2021.1964037
Abstract: Abstract Background Leptin in breast milk play a significant role in metabolic programming. Objective The aim of this study to evaluate the relationship between leptin levels in maternal serum and breast milk, and certain anthropometric… read more here.
Keywords: milk; breast milk; leptin levels; maternal serum ... See more keywords
Association of leptin and adiponectin levels with endometriosis: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2021.1878139
Abstract: Abstract Background We aimed to summarize the available data regarding the levels of leptin and adiponectin and the key modulators of endometriosis compared to the controls. Methods The electronic databases such as MEDLINE, Embase, Scopus,… read more here.
Keywords: levels leptin; women endometriosis; leptin levels; leptin adiponectin ... See more keywords