Mechanisms of reduced leptin-mediated satiety signaling during obesity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Obesity"
DOI: 10.1038/s41366-022-01079-2
Abstract: Disrupted leptin signaling in vagal afferent neurons contributes to hyperphagia and obesity. Thus, we tested the hypothesis that intrinsic negative regulators of leptin signaling, suppressor of cytokine signaling 3 (SOCS3) and protein tyrosine phosphatase 1B… read more here.
Keywords: leptin mediated; satiety; obesity; vagal afferent ... See more keywords
Leptin-mediated neural targets in obesity hypoventilation syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac153
Abstract: Obesity hypoventilation syndrome (OHS) is defined as daytime hypercapnia in obese individuals in the absence of other underlying causes. In the United States OHS is present in 10-20% of obese patients with obstructive sleep apnea… read more here.
Keywords: obesity hypoventilation; hypoventilation syndrome; leptin; hypoventilation ... See more keywords