Diet-Induced Obesity and the Mechanism of Leptin Resistance.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-48382-5_16
Abstract: Leptin signaling blockade by chronic overstimulation of the leptin receptor or hypothalamic pro-inflammatory responses due to elevated levels of saturated fatty acid can induce leptin resistance by activating negative feedback pathways. Although, long form leptin… read more here.
Keywords: leptin resistance; leptin; mechanism leptin; leptin signaling ... See more keywords
The Leptin Resistance.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-1286-1_8
Abstract: Leptin is an adipocyte-derived hormone, which contributes to the homeostatic regulation of energy balance and metabolism through humoral and neural pathways. Leptin acts on the neurons in certain brain areas such as the hypothalamus, hippocampus,… read more here.
Keywords: energy; leptin resistance; leptin; obesity ... See more keywords
Central and peripheral leptin resistance in obesity and improvements of exercise
Sign Up to like & getrecommendations! Published in 2021 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2021.105006
Abstract: Obesity is strongly related to leptin resistance that refers to the state in which leptin fails to inhibit appetite, enhance energy expenditure and regulate glycolipid metabolism, whereas decreasing leptin resistance is important for obesity treatment.… read more here.
Keywords: leptin resistance; central peripheral; resistance; peripheral leptin ... See more keywords
Leptin resistance during pregnancy is also exerted at the peripheryâ€
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy024
Abstract: Abstract Pregnancy is a physiological state with a great demand of energy and nutrients in mammals and is characterized by hyperphagia, increase in fat mass, hyperleptinemia, and central resistance to leptin. In order to evaluate… read more here.
Keywords: state; pregnancy; leptin resistance; leptin ... See more keywords
Leptin Resistance Does Not Facilitate Migratory Fattening in Ruby-Throated Hummingbirds (Archilochus Colubris).
Sign Up to like & getrecommendations! Published in 2023 at "Integrative and comparative biology"
DOI: 10.1093/icb/icad046
Abstract: In mammals, leptin is an important energy homeostasis hormone produced by adipose tissue. Circulating leptin concentrations correlate positively with fat mass and act in a negative feedback fashion to inhibit food intake and increase energy… read more here.
Keywords: leptin; fat mass; food intake; leptin resistance ... See more keywords
Correlations of serum leptin and leptin resistance with depression and anxiety in patients with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12922
Abstract: The associations of serum leptin/soluble leptin receptor (sObR) and leptin resistance with symptoms of depression and anxiety were investigated in patients with type 2 diabetes (T2D). read more here.
Keywords: patients type; leptin resistance; leptin; type diabetes ... See more keywords
The Phlorotannin-Rich Fraction of Ecklonia cava Extract Attenuated the Expressions of the Markers Related with Inflammation and Leptin Resistance in Adipose Tissue
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Endocrinology"
DOI: 10.1155/2020/9142134
Abstract: Obesity is associated with systemic chronic inflammation, and it induces central leptin resistance which blocks the appetite-suppressing effect of leptin and leptin resistance in adipocytes. In the present study, we evaluated the effects of Ecklonia… read more here.
Keywords: leptin resistance; resistance; inflammation; adipose tissue ... See more keywords
A novel anti-obesity mechanism for liraglutide by improving adipose tissue leptin resistance in high-fat diet-fed obese mice.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine journal"
DOI: 10.1507/endocrj.ej21-0802
Abstract: Liraglutide has been approved for the treatment of obesity in the past few years. Both oxidative stress and leptin resistance are the critical drivers of obesity. The present study investigated the mechanism of liraglutide protection… read more here.
Keywords: obesity; mechanism; obese mice; leptin resistance ... See more keywords
Therapeutic Target Analysis and Molecular Mechanism of Melatonin - Treated Leptin Resistance Induced Obesity: A Systematic Study of Network Pharmacology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.927576
Abstract: Background Obesity is a medical problem with an increased risk for other metabolic disorders like diabetes, heart problem, arthritis, etc. Leptin is an adipose tissue-derived hormone responsible for food intake, energy expenditure, etc., and leptin… read more here.
Keywords: induced obesity; pharmacology; analysis; leptin resistance ... See more keywords
The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9100533
Abstract: Obesity is a growing public health problem worldwide. Bariatric surgical procedures achieve the most sustainable and efficacious outcomes in the treatment of morbid obesity. However, little is known about the underlying molecular pathways modulated by… read more here.
Keywords: obesity; leptin resistance; leptin; leptin receptor ... See more keywords
Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?
Sign Up to like & getrecommendations! Published in 2019 at "Nutrients"
DOI: 10.3390/nu11112704
Abstract: Leptin, a hormone that is capable of effectively reducing food intake and body weight, was initially considered for use in the treatment of obesity. However, obese subjects have since been found to have high levels… read more here.
Keywords: leptin obesity; leptin resistance; leptin; obesity ... See more keywords