Doxycycline Attenuates Leptospira-Induced IL-1β by Suppressing NLRP3 Inflammasome Priming
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DOI: 10.3389/fimmu.2017.00857
Abstract: Doxycycline (Dox), a semisynthetic antibiotic, has been reported to exert multiple immunomodulatory effects. Treatment with Dox has a satisfactory curative effect against leptospirosis. In addition to its antibacterial action, we supposed that Dox also modulated… read more here.
Keywords: leptospira induced; dox; nlrp3 inflammasome; inflammasome priming ... See more keywords