Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment
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DOI: 10.1021/acsomega.0c00327
Abstract: A phenotypic whole cell high-throughput screen against the asexual blood and liver stages of the malaria parasite identified a benzimidazole chemical series. Among the hits were the antiemetic benzimidazole drug Lerisetron 1 (IC50 NF54 =… read more here.
Keywords: lerisetron analogues; ic50 nf54; lerisetron; biological assessment ... See more keywords