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Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2018.1504257
Abstract: Abstract The objectives of this study were to determine the absolute bioavailability of lesinurad and to characterized its disposition in humans. The oral bioavailability assessment was performed using a clinical design of simultaneous dosing of…
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Keywords:
disposition;
lesinurad uric;
metabolism disposition;
disposition lesinurad ... See more keywords
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Published in 2017 at "American journal of therapeutics"
DOI: 10.1097/mjt.0000000000000565
Abstract: Successful gout treatment depends almost entirely on lowering serum urate levels.1 Over the last decade, the Food and Drug Administration (FDA) approved 3 new urate-lowering medications: febuxostat, pegloticase, and lesinurad (joining the long-ago-approved drugs allopurinol…
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Keywords:
uric acid;
febuxostat;
trial;
drug ... See more keywords