Cancer Chemoradiotherapy Duo: Nano-Enabled Targeting of DNA Lesion Formation and DNA Damage Response.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b10901
Abstract: Both production of DNA damage and subsequent prevention of its repair are crucial in concluding the therapeutic outcome of radiotherapy (RT). However, nearly all current strategies for improving RT focus only on one of the… read more here.
Keywords: dna damage; lesion formation; dna lesion; dna ... See more keywords
Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22819-3
Abstract: ShcA is an adaptor protein that binds to the cytoplasmic tail of receptor tyrosine kinases and of the Low Density Lipoprotein-related receptor 1 (LRP1), a trans-membrane receptor that protects against atherosclerosis. Here, we examined the… read more here.
Keywords: adhesion; shca; endothelial cells; atherosclerotic lesion ... See more keywords
Durable lesion formation while avoiding esophageal injury during ablation of atrial fibrillation: Lessons learned from late gadolinium MR imaging
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Electrophysiology"
DOI: 10.1111/jce.13426
Abstract: Adequate catheter/atrial tissue contact is critical for lesion formation during radiofrequency (RF) ablation of atrial fibrillation (AF). Late gadolinium enhancement magnetic resonance imaging (LGE‐MRI) is a unique tool for the evaluation of lesion formation and… read more here.
Keywords: atrial fibrillation; ablation atrial; lesion formation; late gadolinium ... See more keywords
Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation
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DOI: 10.1161/atvbaha.118.311092
Abstract: Objective— Vascular remodeling is associated with complex molecular changes, including increased Notch2, which promotes quiescence in human smooth muscle cells. We used unbiased protein profiling to understand molecular signatures related to neointimal lesion formation in… read more here.
Keywords: smooth muscle; lesion; neointimal lesion; lesion formation ... See more keywords
Near-Field Ultrasound Imaging of Ablation Lesion Formation: More Than Meets the Eye?
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DOI: 10.1161/circep.117.006010
Abstract: See Article by Haines et al Effective lesion formation with radiofrequency (RF) catheter ablation in current practice relies on the monitoring of variables which serve as surrogates to tissue destruction. Impedance drop, electrogram diminution, adequacy… read more here.
Keywords: ablation; near field; lesion formation;