Effect of varenicline on behavioral deficits in a rat model of Parkinson’s disease induced by unilateral 6-hydroxydopamine lesion of substantia nigra
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000355
Abstract: Nicotinic acetylcholine receptors (nAChRs) are implicated in the pathogenesis of Parkinson’s disease (PD). Varenicline tartrate is a partial agonist at &agr;4&bgr;2 and full agonist at &agr;7 neuronal nAChR subunits. A unilateral lesion of the substantia… read more here.
Keywords: lesion substantia; behavioral deficits; substantia nigra; effect varenicline ... See more keywords