The impact of NBUVB on microbial community profiling in the lesional skin of vitiligo subjects.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2019.103943
Abstract: BACKGROUND The impact of NBUVB on the cutaneous microbiota of vitiligo patients remains to be fully elucidated. METHODS To characterize the cutaneous microbiota in vitiligo patients, cutaneous samples from 60 patients with vitiligo and after… read more here.
Keywords: diversity; microbial community; group; lesional skin ... See more keywords
Hyperproliferation is the main driver of metabolomic changes in psoriasis lesional skin
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59996-z
Abstract: Systematic understanding of the metabolite signature of diseases may lead to a closer understanding of the disease pathogenesis and ultimately to the development of novel therapies and diagnostic tools. Here we compared for the first… read more here.
Keywords: skin; lesional skin; driver metabolomic; metabolomic changes ... See more keywords
Assessing the severity of psoriasis through multivariate analysis of optical images from non-lesional skin
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65689-4
Abstract: Patients with psoriasis represent a heterogeneous population with individualized disease expression. Psoriasis can be monitored through gold standard histopathology of biopsy specimens that are painful and permanently scar. A common associated measure is the use… read more here.
Keywords: analysis; non lesional; skin; lesional skin ... See more keywords
Structural aspects of lesional and non-lesional skin microbiota reveal key community changes in leprosy patients from India
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80533-5
Abstract: Although skin is the primary affected organ in Leprosy, the role of the skin microbiome in its pathogenesis is not well understood. Recent reports have shown that skin of leprosy patients (LP) harbours perturbed microbiota… read more here.
Keywords: leprosy patients; microbiota; skin; non lesional ... See more keywords
miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1
Sign Up to like & getrecommendations! Published in 2020 at "Hereditas"
DOI: 10.1186/s41065-020-00138-w
Abstract: Background MicroRNAs (miRNAs) target genes involved in the hyperproliferation of keratinocytes or immune dysfunction of psoriasis. This study prospectively determined the involvement of miR-183-3p in the pathogenesis of psoriasis. Methods Differentially expressed miR-183-3p between psoriatic… read more here.
Keywords: mir 183; migration; lesional skin; psoriasis ... See more keywords
Significant Changes in the Skin Microbiome in Patients with Chronic Plaque Psoriasis after Treatment with Narrowband Ultraviolet B.
Sign Up to like & getrecommendations! Published in 2018 at "Acta dermato-venereologica"
DOI: 10.2340/00015555-2859
Abstract: Changes in the skin microbiome have been shown to promote cutaneous inflammation. The skin microbiome of patients with chronic plaque type psoriasis was analysed before and after treatment with narrowband ultraviolet B (UVB). Swab samples… read more here.
Keywords: psoriasis; lesional skin; treatment; skin microbiome ... See more keywords
Effects of Omalizumab on FcεRI and IgE Expression in Lesional Skin of Bullous Pemphigoid
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01919
Abstract: Recent studies suggest an important role of immunoglobulin E (IgE) as an alternative pathogenic pathway in the development of bullous pemphigoid (BP), as the most frequent subepidermal blistering disease of the skin Use of IgE… read more here.
Keywords: skin; bullous pemphigoid; ige expression; lesional skin ... See more keywords
The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.930945
Abstract: Background Recently, the expression of the mast cell (MC) receptor Mas-related G protein–coupled receptor X2 (MRGPRX2) has been detected in lesional skin of adult patients with cutaneous mastocytosis. As of yet, little is known about… read more here.
Keywords: mastocytosis; symptom severity; mrgprx2; lesional skin ... See more keywords
Accumulation of Cytotoxic Skin Resident Memory T Cells and Increased Expression of IL-15 in Lesional Skin of Polymorphic Light Eruption
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.908047
Abstract: Patients with polymorphic light eruption (PLE) develop lesions upon the first exposure to sun in spring/summer, but lesions usually subside during season due to the natural (or medical) photohardening. However, these lesions tend to reappear… read more here.
Keywords: skin; lesional skin; expression; light eruption ... See more keywords
Pruritogenic molecules in the skin of patients with dermatomyositis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1168359
Abstract: Introduction Pruritus is a common excruciating symptom in systemic autoimmune diseases such as dermatomyositis (DM) but the pathogenesis is not fully understood. We intended to investigate the targeted expression analysis of candidate molecules involved in… read more here.
Keywords: lesional skin; non lesional; expression; lesional non ... See more keywords