7,8‐Dihydro‐8‐oxoguanosine Lesions Inhibit the Theophylline Aptamer or Change Its Selectivity
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DOI: 10.1002/cbic.201900684
Abstract: Aptamers are attractive constructs due to their high affinity/selectivity towards a target. Here 7,8‐dihydro‐8‐oxoguanosine (8‐oxoG) has been used, due in part to its unique H‐bonding capabilities (Watson–Crick or Hoogsteen), to expand the “RNA alphabet”. Its… read more here.
Keywords: change; lesions inhibit; dihydro oxoguanosine; oxoguanosine lesions ... See more keywords